Endocrine Abstracts

Introduction: The appearance and normal development of the anterior pituitary gland requires several signalling molecules and specific transcription factors, such as PROP1, POUF1, HESX1/RPX, LHX3, LHX4, PITX2, T-PIT, SOX2 and SOX 3. Gene mutations of these pituitary transcription factors may lead to different degrees of combined pituitary hormone deficiency (CPHD) associated or not with morphological changes of the hypothalamic–pituitary region.Mate...

Introduction: Parathyroid cyst is a very rare abnormality, representing 0.6% of all thyroid and parathyroid lesions. The diagnosis can be made on the basis of sonography and analysis of aspirated cystic fluid for parathyroid hormone. Parathyroid cysts are divided in two groups: functional (associated with clinical hyperparathyroidism) and non-functional. In the case of non-functional parathyroid cysts, fine needle aspiration is the elective treatment, but for functional parath...

Hirsutism may be the expression of hyperandrogenia of ovarian or adrenal origin, iatrogenic or idiopathic/familial. Regardless of the etiology, there is a negative impact of body hair excess on the self-image, the self-esteem and the sexual satisfaction of subjects. The present study aimed to evaluate 60 women, aged 26.3 years, with hirsutism as the primary symptom. At presentation, basal FSH, LH and testosterone levels, urinary 24-hours 17-ketosteroids and DHEA, and an abdomi...